DeSmuME is a small application that allows you to emulate a Nintendo DS system. It has been designed to give you access to numerous tools that allow you to test DS features, from viewing ROM properties to managing Action Replay cheats.
DeSmuME can play Nintendo DS homebrew and commercial NDS ROMs. The emulator itself is in French (with user translations to English and other languages). But even French version of DeSmuME is easy to navigate through menus, as it has a similar user interface to DSemu.
All in all, it's not a bad tool to emulate Nintendo's iconic hand-held machine. It has a basic user interface, that should prove no problems for most users, a few useful tools, the ability to customize screnn resoltion etc, and it can also emulate some of the commercial NDS ROM titles, which other DS Emulators are not able to do.